Status:
COMPLETED
Feasibility and Effectiveness of Community Based Isoniazid Preventive Therapy in Kenya
Lead Sponsor:
KNCV Tuberculosis Foundation
Collaborating Sponsors:
Stichting Mondiale Tuberculose (SMT)
Kenya Medical Research Institute
Conditions:
Tuberculosis
Eligibility:
All Genders
15+ years
Phase:
PHASE4
Brief Summary
Isoniazid preventive therapy (IPT) is a well studied clinical intervention for primary and secondary prevention of active tuberculosis (TB) after infection with Mycobacterium tuberculosis. It is widel...
Eligibility Criteria
Inclusion
- Index cases
- New sputum smear positive pulmonary tuberculosis (PTB) patients initiating treatment for TB
- HIV infected
- Resident in the catchment area of the TB diagnostic facility
- Written informed consent
- Age equal or greater than 15 years.
- Contacts
- Household contacts of a HIV infected smear positive PTB
- No plans to relocate to another area for at least the next two years
- Asymptomatic (Fit) with no cough in last 2 weeks, fever, weight loss (or failure to gain weight in children), haemoptysis or chronic diarrhea at least for the last one month.
- Written informed consent
Exclusion
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
1259 Patients enrolled
Trial Details
Trial ID
NCT00850915
Start Date
April 1 2009
End Date
November 1 2012
Last Update
May 20 2013
Active Locations (18)
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1
Makuyu H/C
Makuyu-Muranga, Central, Kenya
2
Huruma Lions -Central district
Nairobi, Nairobi North, Kenya
3
Kangemi HC
Nairobi, Nairobi North, Kenya
4
Blue House, Mathare
Nairobi, Nairobi South, Kenya