Status:

COMPLETED

Does Threshold IMT Influence Weaning?

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Critical Care

Mechanical Ventilation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Patients under threshold IMT show better conditions to weaning from mechanical ventilation than the control group.

Detailed Description

* After at least 48 hours on CMV, the patients in PSV were randomized into two groups: control group and IMT group. * Before each protocol session, the cardiorespiratory variables such as f, HR, MAP a...

Eligibility Criteria

Inclusion

  • The patients included in this study were under MV for more than 48 hours of CMV and ventilated with pressure support ventilation (PSV) between 12 and 15 cmH2O, with positive end-expiratory pressure (PEEP) between 5 and 7 cmH2O, hemodynamically stable without vasoactive drugs (dopamine, dobutamine or norepinephrine) or sedative agents.

Exclusion

  • This study excluded hypotensive patients (systolic blood pressure \< 100 mmHg or mean blood pressure \< 70 mmHg), severe intracranial disease and sensory reduction, barotrauma, tracheotomy, neuromuscular disease and the use of vasoactive drugs or sedatives.

Key Trial Info

Start Date :

August 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2007

Estimated Enrollment :

92 Patients enrolled

Trial Details

Trial ID

NCT00851617

Start Date

August 1 2004

End Date

July 1 2007

Last Update

March 6 2009

Active Locations (1)

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1

Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil, 90035-903