Status:

COMPLETED

Role of CXCR2 Ligands/CXCR2 Biological Axis in Pancreatic Cancer

Lead Sponsor:

Mayo Clinic

Conditions:

Chronic Pancreatitis

Pancreatic Cancer

Eligibility:

All Genders

18-90 years

Brief Summary

The investigators hypothesize that the CXCR2 ligands/CXCR2 biological axis plays an important role in promoting angiogenesis in PC; and that the genetic changes and the microenvironment of the tumor r...

Eligibility Criteria

Inclusion

  • Normal subjects - No documented clinical history of pancreatic diseases supported by at least 1 negative imaging test. (EUS, Ct scan or MRI)
  • Chronic pancreatitis - Documented diagnosis of moderate to advanced chronic supported bpancreatitisy at least 1 positive imaging test. (EUS, Ct scan or MRI)
  • Pancreatic Cancer - Documented tissue diagnosis (or clinical suspicion) of Pancreatic Cancer.

Exclusion

  • Exclusion criteria will include age younger than 18 yrs, pregnancy, previous pancreatic or gastric resection, and inability to tolerate routine endoscopy with conscious sedation

Key Trial Info

Start Date :

May 1 2007

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2011

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT00851955

Start Date

May 1 2007

End Date

November 1 2011

Last Update

January 12 2016

Active Locations (1)

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Mayo Clinic

Jacksonville, Florida, United States, 32224