Status:
COMPLETED
A Trial of Complete Versus Selective HepaticVascular Clamping in Hepatectomy
Lead Sponsor:
Eastern Hepatobiliary Surgery Hospital
Conditions:
Hepatocellular Carcinoma
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Intraoperative bleeding remains a major concern during liver resection. Pringle maneuver is the most frequently used method to occlude inflow blood of the liver.However, experimental and clinical stud...
Detailed Description
From recent animal studies, it can be easily concluded that I/R injury of the liver may be a significant factor, which can promote the primary liver tumor recurrence and metastasis. If it is a truth i...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- with a clinical diagnosis of primary liver cancer, without any adjuvant therapy;
- age:18-70years;
- suitable for partial hepatectomy without other malignancies;
- compensated cirrhosis with Child-Pugh class A, or B.
- Exclusion criteria:
- reject to attend；
- with any preoperative adjuvant therapy.
- with intrahepatic or extrahepatic malignancies;
- cirrhosis with Child-Pugh class C
Exclusion
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2010
Estimated Enrollment :
320 Patients enrolled
Trial Details
Trial ID
NCT00851968
Start Date
December 1 2008
End Date
December 1 2010
Last Update
April 1 2016
Active Locations (1)
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1
Eastern Hepatobiliary Surgery Hospital
Shanghai, Shanghai Municipality, China, 200438