Status:

COMPLETED

Initial Chronic Human Validation Study: Subcutaneous Implantable Cardioverter Defibrillator (S-ICD) System

Lead Sponsor:

Boston Scientific Corporation

Conditions:

Ventricular Tachyarrhythmias

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Primary objective is to evaluate the safety and performance of the implanted Subcutaneous implantable cardioverter defibrillator (S-ICD) system. A maximum of 10 subjects were to be enrolled and follow...

Eligibility Criteria

Inclusion

  • replacement of an existing transvenous implantable cardioverter defibrillator (ICD) system
  • American College of Cardiology/American Heart Association/Heart Rhythm Society (ACC/AHA/HRS) Class I or II indications for ICD implantation
  • Age \>= 18 years
  • Appropriate pre-operative Electrocardiogram (ECG) as measured with a specially developed template

Exclusion

  • Subjects unable or unwilling to provide informed consent
  • Any condition which precludes the subject's ability to comply with the study requirements
  • Females who are pregnant or lactating and pre-menopausal women who are unwilling to use adequate birth control for the duration of the study
  • Participation in another investigational device trial at any time during the conduct of the S-ICD system trial without written consent from the sponsor.
  • Patients with a serious medical condition and life expectancy of less than one year.
  • Patients with documented spontaneous and frequently recurring ventricular tachyarrhythmias (VT) that is reliably terminated with anti-tachycardia pacing
  • Patients with existing epicardial patches or subcutaneous electrodes in the left thoracic quadrant
  • Patients with chronic renal failure, i.e. with a creatinine level of \>2.5 mg/dl unless prescribed drug therapy known to increase creatinine levels in which case the value should be \<= 3mg/dl

Key Trial Info

Start Date :

July 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2008

Estimated Enrollment :

6 Patients enrolled

Trial Details

Trial ID

NCT00853645

Start Date

July 1 2008

End Date

September 1 2008

Last Update

July 6 2021

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Auckland City Hospital

Auckland, New Zealand, 1001

2

Christchurch Hospital

Christchurch, New Zealand, 8140