Status:
COMPLETED
Enhancement of Motor Function with Reboxetine and Transcranial Direct Current Stimulation
Lead Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Collaborating Sponsors:
German Research Foundation
University Hospital Tuebingen
Conditions:
Cerebral Stroke
Eligibility:
All Genders
18-86 years
Phase:
PHASE4
Brief Summary
The hypothesis of the study is that combination of reboxetine/tDCS is more effective in enhancing motor functions of daily life (assessed by the Jebsen Taylor test) as compared to reboxetine and tDCS ...
Detailed Description
One important feature of the human brain is the ability to undergo plastic changes and reorganization after learning and lesions of the nervous system. This ability is of major importance for the trea...
Eligibility Criteria
Inclusion
- age between 18 and 86
- patient is contractually capable
- first-ever, ischemic stroke
- minimum time since stroke 9 months
- a paresis of the arm/hand muscles above 3 on the MRC scale
Exclusion
- multiple cerebral lesions and associated residual deficits
- severe head trauma in the past
- seizures
- ferromagnetic implants in the head/neck region
- pacemaker
- a psychiatric disorder or neurological disease besides stroke
- intake of illegal drugs
- severe aphasia or cognitive deficits that impede contractual capability
- contraindications for reboxetine (seizures, glaucoma, prostate hyperplasia with urinary retention, cardiac arrhythmias, potential interactions with co-medication)
- pregnancy
- breast-feeding patients
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00853866
Start Date
January 1 2009
End Date
June 1 2010
Last Update
December 10 2024
Active Locations (1)
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1
University Hospital Hamburg-Eppendorf, Department of Neurology
Hamburg, Hamburg, Germany, 20246