Status:
COMPLETED
Long-Term Effects of Aortic Valve Mismatch
Lead Sponsor:
University Hospital, Strasbourg, France
Conditions:
THE LEFT VENTRICULAR REMODELING AFTER MECHANICAL AORTIC VALVE REPLACEMENT
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The real impact of the existence of an aortic valve mismatch after aortic valve replacement in various studies conducted so far is a source of controversy. There is currently no long-term impact of th...
Eligibility Criteria
Inclusion
- Patient major ≤ 60 years at the time of the aortic valve replacement.
- Patient affiliated with a social security
- Consent dated and signed by the investigator and the subject
- Subject having been informed of the results of the visit prior aortic valve replacement by mechanical prosthesis for pure aortic narrowing.
- Fraction left ventricular ejection ≥ 50%, when aortic valve replacement and at the time of inclusion.
- Aortic insufficiency at aortic valve replacement associated \<II / IV.
- aortic valve replacement exclusive (no gestures associated: coronary bypass, enlargement of the ring, another valve surgery,…).
- Coronarography normal at the aortic valve replacement.
- Normal renal function.
- No history of heart failure episode in the previous month inclusion.
- No indication against a stress test on bicycle ergometric
Exclusion
- Refusal of the patient to be included in the study.
- History of cardiac surgery under extra body movement before and / or after the aortic valve replacement.
- Aortic insufficiency associated with the time of the transaction\> II / IV.
- Chronic respiratory insufficiency.
- Track cancer or cancer evolving.
- Evolutionary Osteoarthritis of the lower limbs or widespread.
- Myopathy device.
- Alteration higher making it impossible to carry out the test effort and response to the questionnaire on the quality of life.
- Coronaropathy documented.
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2014
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT00854698
Start Date
June 1 2009
End Date
April 1 2014
Last Update
December 16 2025
Active Locations (1)
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1
CHRU, Nouvel Hôpital Civil, Service de chirurgie cardio-vasculaire
Strasbourg, France