Status:

COMPLETED

Pilot Study for VeinoPlus to Improve Symptoms of Postthrombotic Syndrome (PTS)

Lead Sponsor:

University of North Carolina, Chapel Hill

Collaborating Sponsors:

VeinoPlus USA

Conditions:

Post Thrombotic Syndrome

Deep Vein Thrombosis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The investigators plan to perform an exploratory study to investigate the effects of electro-stimulation of the legs on the symptoms and clinical findings of post thrombotic syndrome (PTS), as well as...

Detailed Description

The purpose of this study is to determine the optimal electrical stimulation intensity level at which subjects using the portable electrical muscle stimulator (VeinoPlus) have the largest benefit for ...

Eligibility Criteria

Inclusion

  • Age \>18
  • Presence of previously objectively documented unilateral, lower extremity deep venous thrombosis
  • Presence of PTS (typical pain and swelling - worse after standing and vertical activity and relieved by rest and the horizontal position), severe enough that the patient is interested to explore a treatment option that might improve these symptoms. Symptoms had to have been stable for ≥ 3 months. Unstable symptoms are defined as: worsening, improving or variable symptoms over preceding months.
  • Subjects must be willing and able to give written informed consent.

Exclusion

  • Inability or refusal to provide informed consent
  • Pregnancy
  • Women of child bearing potential (WOCBP) who are unwilling or unable to use an acceptable method to avoid pregnancy for the entire study period
  • Geographic inaccessibility to prevent scheduled return evaluations
  • Incapable of responding to questionnaires
  • Expected lifespan \<6 months
  • Presence of cardiac pacemaker
  • History of cardiac arrhythmia
  • Presence of infected, or inflamed areas or skin eruptions; phlebitis, thrombophlebitis, active venous ulceration
  • History of seizures

Key Trial Info

Start Date :

March 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2009

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00858130

Start Date

March 1 2009

End Date

November 1 2009

Last Update

November 29 2017

Active Locations (1)

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University of North Carolina at Chapel Hill; University of North Carolina Hospitals

Chapel Hill, North Carolina, United States, 27599