Status:
COMPLETED
Postoperative Pain and SIRS After Preoperative Analgesia With Clonidine or Levobupivacaine
Lead Sponsor:
University Hospital Dubrava
Conditions:
Analgesia
Pain
Eligibility:
All Genders
42-77 years
Phase:
PHASE4
Brief Summary
The purpose of this study was to investigate hypothesis that preoperative administration of epidural clonidine will reduce postoperative pain and systemic inflammatory stress response better than epid...
Detailed Description
Investigations showed that upregulation of prostaglandin E2 and interleukin-6 at central sites is an important component of surgery induced inflammatory response in patients. Postoperative period is a...
Eligibility Criteria
Inclusion
- colorectal resection surgery patients
- preoperative risk of anesthesia and operation, ASA (American Society of Anesthesiologists) physical status I or II
Exclusion
- diabetes mellitus
- renal insufficiency
- liver insufficiency
- autoimmune disease
- corticosteroid and immunosuppressive use
- operation time exceeding six hours
Key Trial Info
Start Date :
December 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2009
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT00860899
Start Date
December 1 2007
End Date
May 1 2009
Last Update
November 17 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Dubrava
Zagreb, Croatia, 10000