Status:
UNKNOWN
Relationships Between Quality of Ageing and Age-related Degenerated Disease (Compalimage)
Lead Sponsor:
University Hospital, Clermont-Ferrand
Collaborating Sponsors:
Centre de Recherche en Nutrition Humaine d'Auvergne
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Conditions:
Age-related Degenerated Disease
Eligibility:
MALE
65+ years
Phase:
NA
Brief Summary
This project aims to assess the impact of chronic micro-inflammation on age-related loss of muscle (sarcopenia) and bone (osteopenia). The hypothesis is that chronic micro-inflammation and oxidative s...
Detailed Description
In order to explore the effect of a moderate chronic inflammation on skeletal muscle function and protein metabolism and on bone status, two groups of 16 subjects each will be selected according to th...
Eligibility Criteria
Inclusion
- Male
- Body mass index 21 BMI 30 kg/m2
- Affiliated to National Health Insurance
- Subject giving his written informed consent
- Subject considered as normal after clinical examination and medical questionnaire.
Exclusion
- Positive serologies to HIV or HCV, determined on blood samples
- Previous medical and/or surgery judged by the investigator as incompatible with this study
- Chronic pathologies : Diabetes, cardiovascular diseases, cancer, chronic inflammation diseases, renal, pulmonary impairments Reported xylocaïne allergy
- Osteoporosis
- Prostate hypertrophy
- Glaucoma
- Heavy consumer of alcohol
- Practising intensive physical exercise
- Being under someone's supervision
- Refusal to be registered on the National Volunteers Data file
- Dietary habits unreliable to controlled food intake
- Being in exclusion on the National Volunteers Data file
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2011
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT00862615
Start Date
January 1 2009
End Date
January 1 2011
Last Update
September 29 2010
Active Locations (1)
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1
CHU Clermont-Ferrand
Clermont-Ferrand, France, 63003