Status:
COMPLETED
Remote Postconditioning in Patients With Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention (PCI)
Lead Sponsor:
Fondazione IRCCS Policlinico San Matteo di Pavia
Conditions:
Myocardial Reperfusion Injury
Myocardial Ischemia
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
PHASE3
Brief Summary
Background: Experimental studies suggest that remote limb ischaemic postconditioning (RemPostCon) can reduce infarct size in pigs. Initial clinical applications support the beneficial role of RemPostC...
Eligibility Criteria
Inclusion
- Age \>= 18 yrs AND Age =\< 80 yrs
- STEMI definition
- Pain to door time \< 6 hrs
- Killip class 1 - 2 - 3
- Initial TIMI flow 0 - 1 in the anterior descending artery
- Signed informed consent
Exclusion
- Pregnancy
- Cardiogenic shock
- Initial TIMI flow 2 - 3 in the anterior descending artery
- History of prior MI in the past 6 months
- History of prior CABG
- History of peripheral vascular disease III - IV grade
- History of abdominal Aortic Aneurysm \> 5 cm
- Severe coronaropathy that could condition further revascularization before the end of the study
- Other relevant medical or surgical conditions that can influence prognosis at 4 months
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2012
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT00865722
Start Date
March 1 2009
End Date
May 1 2012
Last Update
August 17 2012
Active Locations (2)
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1
IRCCS Policlinico San Matteo
Pavia, Italy, Italy, 27100
2
ASL3 Genovese, Villa Scassi Hospitale
Genoa, Italy, 16100