Status:
COMPLETED
Practicing Alternative Techniques to Heal From Depression: The PATH-D Study
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study is a randomized, controlled trial of Mindfulness-Based Cognitive Therapy (MBCT) versus Health-Enhancement Program (HEP) for patients with treatment-resistant major depressive disorder (MDD)...
Eligibility Criteria
Inclusion
- DSM-IV TR Diagnosis of Major Depression receiving medication management.
- Adequate trial of 2 or more antidepressants (ATHF) for a minimum of 6 weeks (one of which at UCSF).
- Hamilton Depression Rating Scale 17 score ≥ 14
- Any Ethnicity
- English Speaking
- Male or Female
- No current psychotherapy (i.e. only medication management treatment) or plan to start new psychotherapy during MBCT or HEP
Exclusion
- Bipolar Disorder, Obsessive Compulsive Disorder, Schizophrenia, Schizoaffective Disorder, Antisocial and Borderline Personality Disorders, Current Eating Disorder, Pervasive Development Delay Major Depression with Psychotic Features
- Active Suicidality (per HAM-D17 \> 1 on item 3)
- Meditation Practice once or more per week; yoga more than twice per week at study entry
- Substance Abuse Disorder within 6 months
- Cognitive Disorder with Mini Mental Status Exam score \< 25
- Medical illness rated 4 on Cumulative Illness Rating Scale
Key Trial Info
Start Date :
September 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
173 Patients enrolled
Trial Details
Trial ID
NCT00871299
Start Date
September 1 2009
End Date
June 1 2014
Last Update
December 2 2014
Active Locations (1)
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1
University of California, San Francisco
San Francisco, California, United States, 94143