Status:
COMPLETED
Pharmacotoxicology of Trichloroethylene Metabolites
Lead Sponsor:
University of Florida
Conditions:
Congenital Lactic Acidosis
Eligibility:
All Genders
21-50 years
Phase:
NA
Brief Summary
To establish the relationship between human MAAI haplotype and DCA and tyrosine metabolism. This aim test the postulates that MAAI haplotype determines, and thus can predict,1) dose-dependent DCA kine...
Detailed Description
The arms of the study involves determining the haplotype of individuals enrolled. Then participants were divided into two groups based on their genotype. The groups include a genotype with an EGT alle...
Eligibility Criteria
Inclusion
- Healthy volunteers
Exclusion
- Pregnancy
- Other medications
- Psychiatric illness on meds
- Abnormal labs
Key Trial Info
Start Date :
August 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT00874276
Start Date
August 1 2009
End Date
November 1 2012
Last Update
June 4 2015
Active Locations (1)
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1
University of Florida Shands Hospital
Gainesville, Florida, United States, 32610