Status:

COMPLETED

Impact of Pre-operative Bevacizumab on Complications After Resection of Colorectal Liver Metastases

Lead Sponsor:

University of Zurich

Conditions:

Colorectal Liver Metastases

Eligibility:

All Genders

18-90 years

Brief Summary

Hypothesis of the study: Neoadjuvant chemotherapy with Bevacizumab impairs postoperative outcome after resection of colorectal liver metastases.

Detailed Description

Bevacizumab is a humanized monoclonal antibody against vascular endothelial growth factor (VEGF) increasingly added to other drugs in the treatment of colorectal cancer. Bev is typically used in combi...

Eligibility Criteria

Inclusion

  • Patients with neoadjuvant chemotherapy prior to liver resection

Exclusion

  • Patients without neoadjuvant chemotherapy

Key Trial Info

Start Date :

April 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2009

Estimated Enrollment :

163 Patients enrolled

Trial Details

Trial ID

NCT00875147

Start Date

April 1 2009

End Date

September 1 2009

Last Update

October 25 2016

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Centre de Chirurgie Viscérale et de Transplantation, Hautepierre Hospital

Strasbourg, Strasbourg, France

2

Division of hepato-biliary-pancreatic surgery. Department of surgery, "Josep Tureta" Hospital

Girona, Girona, Spain

3

University Hospital of Zurich

Zurich, Canton of Zurich, Switzerland, 8091