Status:
COMPLETED
Effect of Calcium Glycerophosphate (CaGP) - Fluoride Dentifrice on Dental Biofilm pH
Lead Sponsor:
Federal University of Paraíba
Collaborating Sponsors:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Coordination for the Improvement of Higher Education Personnel
Conditions:
Dental Caries
Eligibility:
All Genders
19-30 years
Phase:
PHASE1
Brief Summary
The aim of this study was to investigate the buffering effect of a calcium glycerophosphate-fluoride (CaGP-F) dentifrice on in vivo dental biofilm after a cariogenic challenge and evaluate its probabl...
Detailed Description
Although the mechanisms of action of fluoride are reasonably understood, the mechanism of calcium phosphate and calcium glycerophosphate (CaGP) are still a matter of debate. It has been suggested that...
Eligibility Criteria
Inclusion
- to live in a non-fluoridated area
- to have at least 20 natural teeth
- signed a consent form agreeing to carefully follow the research instructions
Exclusion
- presence of active caries lesions
- periodontal disease
- use of antibiotics/medication.
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2008
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00875212
Start Date
January 1 2006
End Date
July 1 2008
Last Update
October 15 2009
Active Locations (1)
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1
Health Science Centre at the Federal University of Paraiba
João Pessoa, Paraíba, Brazil, 58051900