Status:

COMPLETED

Vitamin D Levels in Subjects With Chronic Urticaria and Angioedema

Lead Sponsor:

University of Nebraska

Conditions:

Urticaria

Angioedema

Eligibility:

All Genders

19+ years

Brief Summary

The objective of this study is to perform an exploratory analysis to determine if a possible relationship between vitamin D and chronic urticaria and/or angioedema exists. The study hypothesis is that...

Detailed Description

The purpose of the research protocol is to perform a pilot study to determine the levels of 25-hydroxy vitamin D (25OHD), the storage form of vitamin D, in subjects with chronic urticaria and angioede...

Eligibility Criteria

Inclusion

  • Group 1: subjects with physician-diagnosed allergic rhinitis. Allergic rhinitis is defined by clinical symptoms of sneezing, runny nose, nasal congestion and evidence of IgE-mediated disease (allergy skin prick test positive or radioallergosorbent test \[RAST\] positive to environmental inhalants such as trees, grasses, weeds, animal dander, molds, dust mite, cockroach).
  • Group 2: subjects with physician-diagnosed chronic urticaria and/or angioedema (CUA). CUA is defined by having urticarial wheals (hives) and/or angioedema (dermal swelling) on a daily or almost daily for more than 6 weeks.

Exclusion

  • They are not capable of answering the questionnaire.
  • They are diagnosed with hereditary angioedema. Hereditary angioedema is a genetic disorder, autosomal dominant, of the C1 esterase inhibitor protein. These subjects will be excluded as the etiology of their disease is known.
  • Pregnant or lactating women. All child-bearing women will be asked (verbally and on the questionnaire) if they are pregnant or lactating. If they answer yes, they will be excluded. As there is no risk or harm to the pregnant or lactating woman, a urine pregnancy test will not be used.

Key Trial Info

Start Date :

September 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 11 2009

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT00876369

Start Date

September 1 2009

End Date

December 11 2009

Last Update

September 6 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Nebraska Medical Center

Omaha, Nebraska, United States, 68198