Status:

COMPLETED

The Influence of Soy Isoflavnoids on the Hypocholesterolemic Effects of Soy

Lead Sponsor:

University of Toronto

Conditions:

Hyperlipidemia

Cardiovascular Diseases

Eligibility:

All Genders

21+ years

Phase:

PHASE2

Brief Summary

Isoflavonoids, through their estrogen-like activity, are in part responsible for the cholesterol lowering properties of soy foods. If this is found to be so, then it would be advantageous not only to ...

Eligibility Criteria

Inclusion

  • men and post-menopausal women
  • LDL-C \> 4.1mmol/L at recruitment
  • living within a 40 km radius of St. Michael's Hospital

Exclusion

  • lipid lowering medications
  • clinical or biochemical evidence of diabetes, renal or hepatic disease
  • body mass index (BMI) \>38 kg/m2
  • antibiotic use within the last three months
  • hormone replacement therapy
  • smoking or significant alcohol use (\>1 drink/d)
  • triglyceride level \> 4.0mmol/L

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

End Date :

April 1 2000

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00877825

End Date

April 1 2000

Last Update

April 8 2009

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