Status:
COMPLETED
Sex Differences in Early Brain Development; Brain Development in Turner Syndrome
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Turner Syndrome
Eligibility:
All Genders
2-2 years
Brief Summary
Relative risk for many psychiatric disorders differs dramatically in males and females. Early-onset disorders, such as autism, occur more often in males; other conditions, such as schizophrenia, occur...
Eligibility Criteria
Inclusion
- For controls a child must have a normal ultrasound at the 18 week prenatal visit and the absence of major medical or psychiatric conditions in the mother.
- Children with Turner Syndrome must have diagnosis confirmed by genetic testing.
Exclusion
- For controls - major medical or psychiatric conditions in the mother and major medical problems or congenital conditions in the child.
- For Turner children - The study is open to all TS karyotypes except those with Y chromosome material.
- For both groups children with conditions that preclude participating in an MRI scan ( i.e. metal in the body)
Key Trial Info
Start Date :
October 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
295 Patients enrolled
Trial Details
Trial ID
NCT00877942
Start Date
October 1 2006
End Date
May 1 2014
Last Update
May 2 2014
Active Locations (1)
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1
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States, 27599