Status:
COMPLETED
Functional Magnetic Resonance Imaging (fMRI) and Robot-Assisted Practice of Activities of Daily Living
Lead Sponsor:
Medical College of Wisconsin
Collaborating Sponsors:
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Hemiparesis
Ischemic Stroke
Eligibility:
All Genders
30-85 years
Phase:
PHASE1
Brief Summary
The investigators will study motor recovery after robot-assisted therapy after stroke. A small clinical trial will be conducted to quantify the central nervous system changes associated with robotic o...
Detailed Description
Robot-assisted therapy is on the cutting edge of stroke rehabilitation and is a therapy method that promises to improve the lives of persons with disabilities due to stroke. Preliminary studies using ...
Eligibility Criteria
Inclusion
- Stroke:
- 30 to 85 years
- Right-handed (evaluated with handedness survey)
- suffered a unilateral ischemic stroke in the motor control area, which resulted in hemiparesis of the arm (confirmed by medical data),
- at least 6-months post-stroke
- residual movement at least (a) 15 degree shoulder flexion or adduction, (b) 15 degree active elbow flexion and extension
- not claustrophobic
- not depressed (as measured depression survey)
- able to use the scanner, i.e., passes the fMRI screening survey
- able to understand the instructions and complete the tracking tasks Control
- older than 20 years
- Right-handed (evaluated with survey)
- not claustrophobic
- able to use the scanner, i.e., passes the fMRI screening survey
- able to understand the instructions and complete the tracking tasks
- no history of neurological disorders --not depressed (as measured depression survey)
Exclusion
- Stroke:
- brain stem, stroke
- pre-existing neurological or psychiatric disorders
- Spasticity \>3 at elbow or fingers on Ashworth
- demonstrated visuospatial, language or attention deficits of a severity that prevents understanding the task
- shoulder pain or joint pain during movements
- synkinetic movements or mirror movements
- decline to participate
- will not comply with full protocol
- pregnant
- allergic to goretex and conductivity gel
- Control
- decline to participate
- will not comply with full protocol
- pregnant
- allergic to goretex and conductivity gel
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2013
Estimated Enrollment :
61 Patients enrolled
Trial Details
Trial ID
NCT00878085
Start Date
November 1 2008
End Date
June 1 2013
Last Update
February 4 2014
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
2
Clement J Zablocki VA
Milwaukee, Wisconsin, United States, 53295