Status:
COMPLETED
Antiemetic Prophylaxis for Postdischarge Nausea and Vomiting After Hip Arthroscopy
Lead Sponsor:
Hospital for Special Surgery, New York
Conditions:
Nausea and Vomiting, Postoperative
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
The study is a randomized placebo controlled trial to determine whether repeated postoperative prophylactic ondansetron ("Zofran") administration will prevent postoperative and/or postdischarge nausea...
Eligibility Criteria
Inclusion
- All patients of Dr. Coleman or Dr. Kelly ages 18 to 65 undergoing arthroscopic hip surgery
- Planned use of neuraxial anesthesia
- Ability to follow study protocol
- Willing to complete daily diary and be interviewed daily for three days after discharge
Exclusion
- Patients younger than 18 years old and older than 65
- Patients unable to undergo a spinal or epidural anesthetic
- Having nausea or vomiting within 24 hours of the surgery
- Receiving drugs with anti-emetic properties within 24 hours of the surgery (e.g Zofran, Compazine, Phenergan, Reglan)
- Chronic opioid use (defined as daily or almost daily use of opioids for \>3 months)
- Hypersensitivity and/or allergy to ondansetron
- Intraoperative use of any volatile anesthetic
- Contraindication to a short course of NSAIDs (renal failure, intolerance)
- Allergy or intolerance to Vicodin
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
98 Patients enrolled
Trial Details
Trial ID
NCT00878228
Start Date
April 1 2009
End Date
February 1 2010
Last Update
January 31 2013
Active Locations (1)
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1
Hospital for Special Surgery
New York, New York, United States, 10021