Status:

UNKNOWN

Finding Acute Coronary Syndromes (ACS) With Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms

Lead Sponsor:

Nanosphere, Inc.

Conditions:

Acute Coronary Syndromes

Eligibility:

All Genders

18+ years

Brief Summary

Study Objectives The following items will be prospectively assessed. Primary Endpoints 1. For patients presenting with clinical suspicion of Acute Coronary Syndromes (ACS), high sensitivity-cardiac...

Detailed Description

This study will evaluate the ability of a high sensitivity cardiac troponin I (hs-cTnI) assay to detect and to rule-out high-risk ischemic cardiac injury in emergency room patients experiencing signs ...

Eligibility Criteria

Inclusion

  • The subject must be at least 18 years of age or older.
  • The subject must present to the Emergency Department with symptoms consistent with acute coronary syndromes (e.g., chest discomfort/pain, squeezing/fullness in the chest, pain radiating to left or both arms, jaw pain, pain in back/neck/stomach, shortness of breath, cold sweat, nausea/vomiting, lightheadedness).
  • The subject must present to the Emergency Department within six (6) hours of the onset of the most recent symptoms that prompted the subject to seek medical attention in the Emergency Department.
  • The subject agrees to abide by the protocol, including all telephone follow-up.

Exclusion

  • The subject is in acute distress and requires immediate life-saving intervention.
  • The subject has experienced CPR, defibrillation, or cardioversion within 24 hours of presentation to the Emergency Department.
  • The subject cannot give consent or understand the informed consent form.
  • The subject has a terminal illness (e.g. metastatic cancer) and is not expected to survive 6 months.
  • Patient has trauma related ACS symptoms (i.e. penetrating wounds, crush injury).

Key Trial Info

Start Date :

December 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2011

Estimated Enrollment :

1500 Patients enrolled

Trial Details

Trial ID

NCT00880802

Start Date

December 1 2008

End Date

March 1 2011

Last Update

January 12 2010

Active Locations (16)

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Page 1 of 4 (16 locations)

1

University of California, Davis

Davis, California, United States, 95817

2

University of California San Diego

San Diego, California, United States, 92103

3

Veterans Affairs Medical Center San Diego

San Diego, California, United States, 92161

4

Stanford University

Stanford, California, United States, 94305