Status:
COMPLETED
A Study to Investigate the Efficacy and Safety of Different Doses of Losartan Potassium (MK0954-011)
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Hypertension
Eligibility:
All Genders
21+ years
Phase:
PHASE3
Brief Summary
The purpose of this study was to compare the antihypertensive efficacy of different doses of losartan compared to placebo and enalapril, in patients with supine diastolic blood pressure of 100-115 mmH...
Eligibility Criteria
Inclusion
- Patient has been diagnosed with mild to moderate hypertension, with supine diastolic blood pressure of 100 to 115 mmHg
- Patient has no active medical problems other than essential hypertension that might affect blood pressure
- Patient has received no drug therapy that might affect blood pressure
Exclusion
- Prior exposure to losartan
- History of stroke
- History of myocardial infarction
- Atrial flutter or atrial fibrillation
- History of congestive Heart failure
- Known Sensitivity to ACE inhibitors
- Known positive test for HIV/AIDS or Hepatitis B
- Patient is being treated for acute ulcer disease
- History of chronic liver disease
- Actively treated diabetes mellitis
- Any known bleeding or platelet disorder
- Absence of one kidney
- Women of childbearing potential or who are breastfeeding
- Patient is abusing or has a history of alcoholism or drug addiction
Key Trial Info
Start Date :
December 1 1990
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 1992
Estimated Enrollment :
576 Patients enrolled
Trial Details
Trial ID
NCT00882440
Start Date
December 1 1990
End Date
January 1 1992
Last Update
August 27 2015
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