Status:

UNKNOWN

Assessment of Colonic Permeability by Confocal Laser Endomicroscopy

Lead Sponsor:

Shandong University

Conditions:

Inflammatory Bowel Disease

Ulcerative Colitis

Eligibility:

All Genders

18-80 years

Brief Summary

The purpose of this study is to evaluate the efficacy of confocal laser endomicroscopy in assessment of colonic permeability against conventional sugar absorption test.

Detailed Description

Increased intestinal permeability has been shown significant in many gastrointestinal diseases, including inflammatory bowel disease and recently irritable bowel syndrome. The conventional test method...

Eligibility Criteria

Inclusion

  • Patients with history of ulcerative colitis
  • Bowel habits alterations meeting IBS diagnosis criteria and indications for colonoscopy investigation
  • Asymptomatic individuals for health surveillance or patients for follow up after polypectomy
  • Patients complained of hemafecia but colonoscopy revealed only haemorrhoid

Exclusion

  • Known cancers or abdominal surgery
  • Scheduled for endoscopic treatment
  • Alarm symptoms such as anaemia, gastrointestinal bleeding or obstruction, marked weight loss, abdominal mass
  • Under conditions such as:
  • ascites
  • jaundice
  • liver cirrhosis
  • impaired renal function
  • coagulopathy
  • fever
  • pregnancy
  • breastfeeding
  • Inability to provide informed consent
  • Known allergy to fluorescein sodium

Key Trial Info

Start Date :

April 1 2009

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2009

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00883077

Start Date

April 1 2009

End Date

December 1 2009

Last Update

October 14 2009

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Department of Gastroenterology, Qilu Hospital, Shandong University

Jinan, Shandong, China, 250012