Status:
COMPLETED
Estimation of Functional Liver Reserve Using Cholinesterases
Lead Sponsor:
University of Milan
Conditions:
Hepatocellular Carcinoma
Cirrhosis
Eligibility:
All Genders
18-90 years
Brief Summary
Estimation of functional liver reserve in patients with hepatocellular carcinoma (HCC) in cirrhosis is of paramount importance to properly select candidates for surgical resection. Together with the v...
Eligibility Criteria
Inclusion
- Total bilirubin \< 2 mg/dl
- No ascites
- No esophageal varices, or esophageal varices eradicated by endoscopy
- Liver volume:
- residual liver volume \> or = 40% if total bilirubin \< 1 mg/dl
- residual liver volume \> or = 50% if total bilirubin between 1 and 1.5 mg/dl
- only limited resection if total bilirubin \> 1.5 mg/dl
- Portal vein embolization was selected in any case in whom RLV did not fit the previous requirements.
Exclusion
- Total bilirubin \> 2 mg/dl
- Refractory ascites
- Esophageal varices
Key Trial Info
Start Date :
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
181 Patients enrolled
Trial Details
Trial ID
NCT00883454
Last Update
April 17 2009
Active Locations (1)
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1
Liver Surgery Unit, Third Department of Surgery, University of MIlan, IRCCS Istituto Clinico Humanitas
Rozzano, Milan, Milan, Italy, 20089