Status:
UNKNOWN
The Effects of Preconditioning on Intramuscular High-Energy Phosphate Levels During Ischemia
Lead Sponsor:
Medical University of Vienna
Conditions:
Ischemia
Eligibility:
MALE
18-45 years
Phase:
NA
Brief Summary
Ischemia reperfusion injury may be reduced by ischemic preconditioning. This projects aims to show the effects of short and long time ischemic preconditioning (both sequences 3 x 5 minutes) during and...
Eligibility Criteria
Inclusion
- Men aged between 18 and 45 years
- Nonsmoker for more than 3 months
- Body mass index between 18 and 25 kg/m2
- Normal findings in medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant
Exclusion
- Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
- Evidence of hypertension, pathologic hyperglycemia, hyperlipidemia
- Treatment in the previous 3 weeks with any drug including over-the-counter drugs
- Symptoms of a clinically relevant illness in the 2 weeks before the first study day
- Blood donation during the previous 3 weeks
- Any metallic, electric, electronic or magnetic device or object not removable
- Claustrophobia
Key Trial Info
Start Date :
May 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00883467
Start Date
May 1 2008
Last Update
April 17 2009
Active Locations (1)
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1
Medical University of Vienna, Department of Clinical Pharmacology
Vienna, Austria, 1090