Status:
TERMINATED
Polycystic Ovary Syndrome (PCOS) and In Vitro Fertilization (IVF): A Comparison Between Standard Long Protocol Versus an Antagonist Protocol Starting on Day 1
Lead Sponsor:
Fundacion Dexeus
Conditions:
Polycystic Ovary Syndrome
In Vitro Fertilization
Eligibility:
FEMALE
18-37 years
Phase:
NA
Brief Summary
The aim of this study is to compare two different IVF-stimulation protocols in patients affected by PCOS: the use of a Gonadotropin-releasing hormone (GnRH) - antagonist starting on day 1 of controlle...
Detailed Description
Hejinen et al (1) recently conducted a meta-analysis to compare outcomes of conventional IVF in women presenting with polycystic ovary syndrome (PCOS) and non-PCOS patients. They compared nine RCTs re...
Eligibility Criteria
Inclusion
- PCOS patients according to the Rotterdam consensus criteria
- Presence of both ovaries
- Absence of endometriomas detected at ultrasound
- FSH \< 10 IU/L on day 3 of the cycle
- E2 \< 80 pg/mL, and Pg \< 1.6 ng/mL at initiation of stimulation
Exclusion
- Congenital adrenal hyperplasia
- Cushing's syndrome
- Androgen-producing tumours
- Hyperprolactinaemia and thyroid dysfunction
- Age \> 38 years
- Serum FSH levels \> 10 mIU/ml
Key Trial Info
Start Date :
April 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2012
Estimated Enrollment :
172 Patients enrolled
Trial Details
Trial ID
NCT00883766
Start Date
April 1 2009
End Date
June 1 2012
Last Update
July 20 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Institut Universitari Dexeus
Barcelona, Barcelona, Spain, 08028