Status:
COMPLETED
Microorganism in Overactive Bladder Patients
Lead Sponsor:
Samsung Medical Center
Conditions:
Overactive Bladder
Eligibility:
FEMALE
20-80 years
Phase:
PHASE4
Brief Summary
The objective of this prospective study is to determine the incidence of mycoplasma in women with overactive bladder (OAB) symptoms and whether antibiotic therapy targeting these organisms is effectiv...
Detailed Description
Overactive bladder (OAB) syndrome is described as 'urgency, with or without urge incontinence, usually with frequency and nocturia' by the 2002 ICS Terminology Committee. A variety of medical conditio...
Eligibility Criteria
Inclusion
- Women age of 20 ≤ and ≤ 80 years
- Symptoms of urinary frequency (≥8 micturitions per 24 hours) and urinary urgency (defined as a level of 3 to 5 in a 5 point urgency scale) at least one episode a day as verified by baseline micturition diary
- Symptoms of overactive bladder, including, urgency, frequency, and/or urinary urge incontinence for more than 3 months
- No proven ordinary bacteria on routine urine culture or gram stain
- Positive for one of Mycoplasma homonis, Ureaplasma Urealyticum and Chlamydia trachomatis on urethral or cervical swab
Exclusion
- Neurogenic bladder
- Indwelling catheter
- PVR ≥ 150ml
- Interstitial cystitis
- History of radiation therapy on pelvic area or chemotherapy
- unable to record voiding diary
- Pregnancy
- Other reasons according to investigator's opinion
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT00883818
Start Date
January 1 2007
End Date
December 1 2007
Last Update
July 7 2009
Active Locations (3)
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1
Inha University College of Medicine
Inchon, South Korea
2
Kangnam St. Mary's Hospital, The Catholic University of Korea
Seoul, South Korea, 137-701
3
Asan Medical Center, Ulsan College of Medicine
Seoul, South Korea