Status:
COMPLETED
Effect of Reward on Learning in Motor Cortex
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborating Sponsors:
United States Department of Defense
National Institutes of Health Clinical Center (CC)
Conditions:
Healthy
Eligibility:
All Genders
18-50 years
Brief Summary
Background: * Magnetic resonance imaging (MRI) uses a strong magnetic field and radio waves to take pictures of the brain. Some MRI studies suggest that this technique reveals brain differences in pa...
Detailed Description
Objective: The role of mesencephalic dopamine neurons in reward processing has been established in primates using electrophysiological techniques and in humans using functional neuroimaging. They have...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Age 18-50.
- Right handed.
- EXCLUSION CRITERIA:
- Significant neurological or psychiatric history
- Habitual consumption of more than two drinks a day, marijuana more than once a week or any other illicit drug use within the last three months
- Use of medication affecting the DA system, such as phenothiazine antihistamines (promethazine), antiemetics or decongestants within the last month
- Significant abnormality on neurological examination
- Metal in the cranial cavity or eye, pacemaker, implanted pumps or stimulators
- Subjects who participate in any one experiment in this protocol may not participate in another experiment in this protocol.
Exclusion
Key Trial Info
Start Date :
April 15 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 22 2013
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT00885131
Start Date
April 15 2009
End Date
January 22 2013
Last Update
December 9 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892