Status:

COMPLETED

Prevention of the Hepatic Sinusoidal Obstruction Syndrome by Means of Anticoagulants

Lead Sponsor:

Maastricht University Medical Center

Conditions:

Sinusoidal Obstruction Syndrome

Colorectal Liver Metastases

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of the study is to determine whether anticoagulant use (i.e. salicylates, clopidogrel, low-molecular weight heparin, or coumarin derivates) is able to prevent the development of the sinuso...

Detailed Description

Surgical resection remains the only curative treatment for patients suffering from colorectal liver metastases, but only 15-25% of patients are initially eligible for resection. The majority of patien...

Eligibility Criteria

Inclusion

  • age \> 18 years
  • colorectal liver metastases that are eligible for resection
  • operated from January 2008 up until December 2009 at Maastricht University Medical Centre

Exclusion

  • irresectable colorectal liver metastases

Key Trial Info

Start Date :

January 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2010

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT00885950

Start Date

January 1 2008

End Date

June 1 2010

Last Update

February 4 2014

Active Locations (1)

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1

Department of Surgery; Maastricht University Medical Centre

Maastricht, Netherlands