Status:

COMPLETED

The Comparison of Efficacy for Cervical Ripening in Labor Induction Between Titrated and Conventional Oral Misoprostol

Lead Sponsor:

Mahidol University

Conditions:

Cervical Ripening

Labor Induction

Eligibility:

FEMALE

18-45 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to compare the efficacy for cervical ripening in labor induction between titrated and conventional oral misoprostol

Eligibility Criteria

Inclusion

  • age 18 years old or more
  • singleton pregnancy at 37 weeks gestation or more
  • cephalic presentation
  • reassuring fetal heart rate pattern
  • admission for labor induction due to medical or obstetrical conditions
  • bishop score less than 6
  • giving consent and having signed the consent form for this study

Exclusion

  • parity more than 3
  • estimated fetal weight more than 3,500 grams
  • non-reassuring fetal heart rate pattern
  • having contraindication for vaginal delivery
  • previous uterine scar
  • suspected abruptio placenta with non-reassuring fetal heart rate pattern
  • abnormal bleeding per vagina, except bloody show
  • PROM
  • having underlying cardiac, hepatic, or renal diseases
  • having history of allergy to misoprostol or prostaglandin analogues
  • cervical dilatation 3 centimeters or more
  • uterine contraction 3 times or more in 10 minute

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2010

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT00886860

Start Date

May 1 2009

End Date

March 1 2010

Last Update

July 14 2010

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Siriraj Hospital, Mahidol University

Bangkok, Bangkok, Thailand, 10700