Status:
COMPLETED
A Study to Investigate the Antihypertensive Efficacy of MK0954
Lead Sponsor:
Merck Sharp & Dohme LLC
Conditions:
Hypertension
Eligibility:
All Genders
21+ years
Phase:
PHASE3
Brief Summary
After a 4 week placebo period, patients were randomized to Placebo or Losartan 50 mg arms, after 6 weeks non-responders were up titrated to 100 mg losartan for the remaining 6 weeks. This study evalua...
Eligibility Criteria
Inclusion
- Patient has been diagnosed with mild to moderate hypertension (SDBP 95-115 mm Hg)
- Patient has no medical problems or treatments that might effect their blood pressure
Exclusion
- Pregnant or lactating females
- Patient has secondary hypertension or malignant hypertension
- Sitting systolic blood pressure \> 210 mm Hg
- History of stroke
- History of myocardial infarction with in past year
- Current or prior history of heart failure
- Known hypersensitivity to losartan
- Prior exposure to losartan
- Patients known to be HIV positive
- Patient is abusing or has abused alcohol or other drugs within the past 4 years
Key Trial Info
Start Date :
December 1 1991
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 1992
Estimated Enrollment :
366 Patients enrolled
Trial Details
Trial ID
NCT00887250
Start Date
December 1 1991
End Date
November 1 1992
Last Update
July 14 2009
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