Status:

UNKNOWN

Single Dose Steroid Before Thyroidectomy for Benign Disease to Improve Postoperative Nausea, Pain, and Vocal Function

Lead Sponsor:

Ospedale Misericordia e Dolce

Conditions:

Postoperative Pain

Postoperative Nausea and Vomit

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to evaluate the efficacy of 8 mg of dexamethasone administered prior surgery, to reduce pain, postoperative nausea and vomiting and to improve vocal function after thyroid...

Eligibility Criteria

Inclusion

  • Age \> 18 years
  • Patients undergoing thyroidectomy

Exclusion

  • Patients who had received antiemetic therapy within 48 hours before surgery
  • Patients with depression
  • Chronic pain disorder
  • Insulin-dependent diabetes mellitus
  • History of severe and/or repeated PONV after previous minor surgery, that led to change from standard anesthetic protocol
  • Pregnancy
  • Age \< 18 years
  • Patients who had known malignant disease or had undergone previous thyroid or neck surgery

Key Trial Info

Start Date :

January 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2012

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT00888303

Start Date

January 1 2009

End Date

October 1 2012

Last Update

September 5 2012

Active Locations (1)

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Misericordia and Dolce Hodpital

Prato, Po, Italy, 59100