Status:

COMPLETED

MK0954 Versus Placebo for Treatment of Mild to Moderate Hypertension

Lead Sponsor:

Merck Sharp & Dohme LLC

Conditions:

Hypertension

Eligibility:

All Genders

21+ years

Phase:

PHASE3

Brief Summary

The study had a 4 week single blind placebo period followed by 12 weeks of double blind treatment. Patients were randomized to one of four treatment arms to evaluate the antihypertensive efficacy of L...

Eligibility Criteria

Inclusion

  • Patient has been diagnosed with mild to moderate hypertension
  • Patient has no treatment or active medical problem, other than hypertension that might affect the patients blood pressure

Exclusion

  • Pregnant of lactating female patients
  • Secondary hypertension or history of malignant hypertension
  • Sitting systolic blood pressure \> 210 mmHg
  • History of stroke
  • History of myocardial infarction with in the past year
  • Current of prior history of heart failure
  • Known hypersensitivity to losartan
  • Obesity
  • Patients known to be HIV positive or known to be positive for Hepatitis B
  • Absence of one kidney
  • Patient is abusing or previously abused alcohol or drugs with in past two years

Key Trial Info

Start Date :

May 1 1992

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 1993

Estimated Enrollment :

428 Patients enrolled

Trial Details

Trial ID

NCT00888355

Start Date

May 1 1992

End Date

February 1 1993

Last Update

July 9 2009

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MK0954 Versus Placebo for Treatment of Mild to Moderate Hypertension | DecenTrialz