Status:

COMPLETED

Satiety Response After Mixed Fiber Doses

Lead Sponsor:

University of Minnesota

Collaborating Sponsors:

Société des Produits Nestlé (SPN)

Conditions:

Satiety

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

People who eat more dietary fiber have a lower body weight than people who eat less fiber. Potential mechanisms include greater feelings of satiety, reductions in food intake, changes in blood glucose...

Eligibility Criteria

Inclusion

  • English speaking
  • healthy men and women
  • 18 and 65 years of age
  • non-smoking
  • not taking medications
  • non-dieting (weight stable over last 3 months)
  • BMI between 18 and 27
  • able to give blood through an IV

Exclusion

  • irregular or erratic breakfast eating patterns
  • food allergies to ingredients commonly found in muffins or pizza
  • distaste for muffins or pizza
  • BMI less than 18 or greater than 27
  • weight change \> 5 kg in last 3 months (intentional or unintentional)
  • cardiovascular disease
  • diabetes mellitus (fasting blood sugar \> 126 mg/dl)
  • cancer in prior 5 years (except basal cell carcinoma of skin)
  • renal or hepatic disease
  • Crohns disease
  • ulcerative colitis
  • any other gastrointestinal conditions that may affect digestion or absorption
  • recent bacterial infection (\< 3 months)
  • chronic medication use
  • history of drug or alcohol abuse in prior 6 months
  • concurrent or recent intervention study participation
  • vegetarians
  • people who ate more than approximately 15 g of fiber per day
  • pregnant or lactating women
  • women with irregular menstrual cycles

Key Trial Info

Start Date :

November 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2008

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00889993

Start Date

November 1 2007

End Date

October 1 2008

Last Update

March 29 2012

Active Locations (1)

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University of Minnesota: General Clinical Research Center

Minneapolis, Minnesota, United States, 55455