Status:

COMPLETED

A Study of Meropenem Standard 30 Minute Infusion Versus Prolonged 3 Hour Infusion in Intensive Care Unit (ICU) Patients

Lead Sponsor:

Austin Health

Conditions:

Sepsis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Meropenem is a powerful antibiotic used in intensive care for people who have very serious infections. Meropenem is rapidly removed from the blood by the kidneys and it is very expensive. In very ill ...

Detailed Description

The use of pharmacodynamic and pharmacokinetic principles in antibiotic dosing is advocated to enable more effective and efficient use of antibiotics. The current standard of care in Austin ICU is to...

Eligibility Criteria

Inclusion

  • Adult intensive care patients
  • Predicted duration of treatment 3 days or more

Exclusion

  • Predicted duration of treatment less than 3 days
  • Hypersensitivity to meropenem or other beta-lactams
  • Consent unable to be obtained by participant or next of kin
  • Suspected or proven bacterial meningitis

Key Trial Info

Start Date :

April 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2010

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT00891423

Start Date

April 1 2009

End Date

January 1 2010

Last Update

August 3 2015

Active Locations (1)

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1

Austin Health

Melbourne, Victoria, Australia, 3084