Status:
UNKNOWN
Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade Glioma
Lead Sponsor:
Children's Cancer and Leukaemia Group
Conditions:
Brain and Central Nervous System Tumors
Eligibility:
All Genders
Brief Summary
RATIONALE: Studying samples of tumor tissue and blood in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors ...
Detailed Description
OBJECTIVES: * To develop a better understanding of why low-grade glioma tumors develop in children and adolescents. * To study genetic profiles that may predict response to treatment and provide clue...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Biological parents of a child or adolescent patient diagnosed with low grade glioma (LGG)
- LGG patients participating in 1 of the following clinical trials:
- On active follow up for study SIOP-LGG1 at a Children's Cancer and Leukemia Group center
- On study SIOP-LGG-2004
- Adoptive parents or guardians allowed if they feel they have the knowledge to complete the study questionnaire, provided either or both biological parents are unable to complete the questionnaire
- PATIENT CHARACTERISTICS:
- Not specified
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
900 Patients enrolled
Trial Details
Trial ID
NCT00891722
Start Date
August 1 2008
Last Update
August 26 2013
Active Locations (1)
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1
Queen's Medical Centre
Nottingham, England, United Kingdom, NG7 2UH