Status:

ACTIVE_NOT_RECRUITING

Partial Breast Versus Whole Breast Irradiation in Elderly Women Operated on for Early Breast Cancer

Lead Sponsor:

Danish Breast Cancer Cooperative Group

Collaborating Sponsors:

Danish Center for Interventional Research in Radiation Oncology (CIRRO)

Danish Cancer Society

Conditions:

Breast Carcinoma

Eligibility:

FEMALE

60+ years

Phase:

NA

Brief Summary

The purpose of this trial is to investigate the difference in late radiation morbidity between partial breast irradiation and whole breast irradiation given to women operated on with breast conservati...

Detailed Description

The study is 2-armed. In both treatment arms the radiotherapy consists of 40 Gy in 15 fractions, 2.67 Gy per fraction. The primary endpoint in the trial is late radiation morbidity evaluated as fibros...

Eligibility Criteria

Inclusion

  • women 60 years or older
  • operated for unilateral, unifocal early breast cancer pT1, pN0, M0, grade I or II, positive estrogen and/or progesterone receptor, HER2 negative

Exclusion

  • lobular carcinoma

Key Trial Info

Start Date :

May 14 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2026

Estimated Enrollment :

882 Patients enrolled

Trial Details

Trial ID

NCT00892814

Start Date

May 14 2009

End Date

March 1 2026

Last Update

February 25 2020

Active Locations (1)

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The Danish Breast Cancer Cooperative Group

Copenhagen, Copenhagen Ø, Denmark, DK-2100