Status:

COMPLETED

Levocetirizine Effect on Nasal Nitric Oxide and Nasal Eosinophils in Subjects With Perennial Allergic Rhinitis

Lead Sponsor:

AAADRS Clinical Research Center

Collaborating Sponsors:

UCB Pharma

Conditions:

Perennial Allergic Rhinitis

Eligibility:

All Genders

12-65 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to noninvasively measure the anti-inflammatory effect of levocetirizine after two weeks of treatment in allergic rhinitis subjects.

Eligibility Criteria

Inclusion

  • ICF signed
  • Diagnosis of PAR for 6-12 months greater
  • 12 years and older
  • Decreased nasal NO values at baseline
  • Compliance and ability to perform maneuvers and responsibilities

Exclusion

  • Oral or systemic steroids for 60 days prior
  • Inhaled, nasal, nebulized steroids w/i 4 weeks
  • Hospitalization or life threatening asthma
  • Use of nasal or oral antihistamines w/i 4 weeks
  • Upper or lower airways infection
  • Direct cigarette smoke exposure

Key Trial Info

Start Date :

January 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2009

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT00894231

Start Date

January 1 2009

End Date

August 1 2009

Last Update

September 4 2009

Active Locations (1)

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AAADRS

Coral Gables, Florida, United States, 33134