Status:

COMPLETED

Performance Evaluation of the AMS CONTINUUM™ Device

Lead Sponsor:

American Medical Systems

Conditions:

Prostate Cancer

Eligibility:

MALE

40+ years

Phase:

NA

Brief Summary

1. To assess the safety of using the CONTINUUM™ device by monitoring the side effects and complications associated with the Device following a radical prostatectomy. 2. To verify CONTINUUM™ device per...

Detailed Description

Surgery is the main treatment for localized prostate cancer. The most common technique is a "radical prostatectomy," which involves removing the prostate gland, seminal vesicles and nearby lymph nodes...

Eligibility Criteria

Inclusion

  • All males ≥ 40 years old who are indicated for a radical prostatectomy will be eligible to participate in the study.
  • The Subject is willing and able to return for study follow-up visits according to the protocol.
  • The Subject can be off diuretics and blood thinners for at least one week prior to surgery.

Exclusion

  • If contraindicated for surgery
  • Inability to understand the study or a history of non-compliance with medical advice
  • Unwilling or unable to sign an Informed Consent Form (ICF)
  • Participation in another clinical trial
  • Previously implanted urological device
  • A history of Recurrent urinary tract infections (UTI)
  • A history of stricture disease
  • Prior invasive prostate treatments (e.g., TURP, TUIP, laser therapy, radiotherapy, cryotherapy)
  • Neurological disease with a history of bladder dysfunction (e.g., Parkinson's disease)
  • Uncontrolled insulin-dependent diabetes
  • Chemotherapy within the past 6 months
  • Non-topical steroid use within the past 6 months
  • History of connective tissue or autoimmune conditions
  • Compromised immune system
  • Allergy to nitinol, nickel, titanium or silicone
  • Body Mass Index greater than or equal to 30
  • American Society of Anesthesiologists Score of \> 3
  • Prostate size greater than or equal to 50 grams as determined by TRUS

Key Trial Info

Start Date :

May 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2010

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT00894933

Start Date

May 1 2009

End Date

December 1 2010

Last Update

February 22 2018

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Arkansas Urology

Little Rock, Arkansas, United States, 72211

2

Lahey Clinic Medical Center

Burlington, Massachusetts, United States, 01805

3

Center for Urology

Rochester, New York, United States, 14619

4

Urologic Consultants of Southeastern Pennsylvania

Philadelphia, Pennsylvania, United States, 19004