Status:
UNKNOWN
Trial of Concurrent Versus Sequential Tamoxifen With Radiotherapy in Breast Cancer Patients
Lead Sponsor:
Tata Memorial Hospital
Collaborating Sponsors:
Indian Council of Medical Research
Conditions:
Pulmonary Fibrosis
Breast Cancer
Eligibility:
FEMALE
Phase:
PHASE3
Brief Summary
Two hundred and sixty patients with breast cancer will be accrued into the study. After inclusion in the study, all the patients will be randomized into two arms. Arm 1 will receive Tamoxifen given co...
Eligibility Criteria
Inclusion
- Patients with large operable lesions (pT/cT \> 5 cm) or locally advanced breast cancers undergoing modified radical mastectomy or breast conservative surgery-(BCS) who need adjuvant post operative radiotherapy
- Patients post mastectomy requiring radiotherapy because of nodal positivity
- Completed planned chemotherapy schedule
- ER and/or PR positive patients
- Patients decided to be put on tamoxifen
- Patients reliable for follow up
Exclusion
- Patients with BCT who have pT1 or pT2 breast lesions (N0,N1)
- Patients for palliative radiotherapy to the chest wall/breast/supraclavicular fossa
- Any patient requiring radiation to the axillary or internal mammary area
- Recurrent disease or metastatic disease
- Patients on concurrent chemotherapy and radiation
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2013
Estimated Enrollment :
260 Patients enrolled
Trial Details
Trial ID
NCT00896155
Start Date
December 1 2008
End Date
December 1 2013
Last Update
August 30 2011
Active Locations (1)
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1
Tata Memorial Center
Pārel, Mumbai, India, 400012