Status:

UNKNOWN

Therapeutic Efficacy of Oral L-Ornithine-L-Aspartate on Minimal Encephalopathy

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Hepatic Encephalopathy

Eligibility:

All Genders

18-70 years

Phase:

PHASE4

Brief Summary

The study aimed to assess the effectiveness and safety of L-ornithine-L-aspartate in the management of hepatic encephalopathy.

Detailed Description

Hepatic encephalopathy continues to be a major clinical problem in cirrhosis. Patients with minimal hepatic encephalopathy are at risk for accidents, had a decline in work performance, or complain of ...

Eligibility Criteria

Inclusion

  • Cirrhosis and diagnosis of minimal hepatic encephalopathy using psychometric tests and critical flicker frequency

Exclusion

  • Hepatic encephalopathy grade 1 to 4
  • Use of drugs to treatment of hepatic encephalopathy (lactulose, neomycin)
  • Psychoactive substance use within 72 hours

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2010

Estimated Enrollment :

96 Patients enrolled

Trial Details

Trial ID

NCT00896831

Start Date

November 1 2008

End Date

September 1 2010

Last Update

June 10 2009

Active Locations (1)

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1

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, Brazil