Status:

COMPLETED

Immunoreactivity to Cetuximab in Cancer Patients

Lead Sponsor:

Vanderbilt-Ingram Cancer Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Colorectal Cancer

Head and Neck Cancer

Eligibility:

All Genders

18-75 years

Brief Summary

RATIONALE: Studying samples of blood in the laboratory may help doctors predict which patients will develop hypersensitivity to cetuximab. PURPOSE: This research study is looking at hypersensitivity ...

Detailed Description

OBJECTIVES: * To examine serum samples from patients with head and neck cancer or advanced colorectal cancer previously treated with cetuximab for the presence of antibodies against cetuximab. OUTLI...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of one of the following:
  • Head and neck cancer
  • Advanced colorectal cancer
  • Previously treated with cetuximab
  • Serum samples available from patients enrolled in one of the following clinical trials:
  • VU-VICC-GI-0410 (colorectal cancer)
  • VU-VICC-GI-0622 (colorectal cancer)
  • VU-VICC-HN-0356 (head and neck cancer)
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    November 1 2006

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    October 1 2008

    Estimated Enrollment :

    538 Patients enrolled

    Trial Details

    Trial ID

    NCT00896896

    Start Date

    November 1 2006

    End Date

    October 1 2008

    Last Update

    April 2 2013

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