Status:
COMPLETED
Study of Metabolic Syndrome in Young Patients Who Are Acute Lymphoblastic Leukemia Survivors and Their Healthy Siblings
Lead Sponsor:
Vanderbilt University
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Leukemia
Eligibility:
All Genders
8-21 years
Brief Summary
RATIONALE: Gathering information about metabolic syndrome from young patients who have survived acute lymphoblastic leukemia (ALL) may help doctors learn more about the disease. PURPOSE: This phase I...
Detailed Description
OBJECTIVES: * Determine the prevalence of the metabolic syndrome (MS) and its component traits (i.e., obesity, hypertension, dyslipidemia, and insulin resistance) in survivors of childhood acute lymp...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Meets one of the following eligibility criteria:
- Childhood acute lymphoblastic leukemia survivor
- Less than 22 years old at diagnosis
- Treated from 1990-2007 at one of the following locations:
- Fred Hutchinson Cancer Research Center and/or Children's Hospital and Regional Medical Center in Seattle, WA
- Vanderbilt Children's Hospital in Nashville, TN
- Meets 1 of the following treatment criteria:
- Completed conventional therapy ≥ 11 months ago and in first complete remission
- Received an allogeneic hematopoietic cell transplantation ≥ 11 months ago and in complete remission
- No evidence of recurrent disease
- Healthy volunteer
- Full sibling of enrolled cancer survivor
- Age 8-21 (if more than 1 eligible sibling, sibling of closest age is preferred)
- No history of cancer
- PATIENT CHARACTERISTICS:
- Able to speak, read, and write English
- PRIOR CONCURRENT THERAPY:
- See Disease Characteristics
- No active treatment for graft-vs-host disease
Exclusion
- Lack of ability to speak, read, and write English
- Active treatment for graft versus host disease
Key Trial Info
Start Date :
January 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT00897078
Start Date
January 1 2009
End Date
October 1 2011
Last Update
June 13 2013
Active Locations (2)
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1
Vanderbilt-Ingram Cancer Center - Cool Springs
Nashville, Tennessee, United States, 37064
2
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States, 37232-6838