Status:

COMPLETED

Identifying Cancer Genes in in Blood and Bone Marrow Samples From Patients With Acute Myeloid Leukemia

Lead Sponsor:

Alliance for Clinical Trials in Oncology

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

Brief Summary

RATIONALE: Studying samples of blood and bone marrow in the laboratory from patients with cancer may help doctors learn more about changes that occur in DNA and identify genes related to cancer. It ma...

Detailed Description

OBJECTIVES: * To identify and validate individual genes for diagnosis of three major translocations in acute myeloid leukemia. * To correlate transcript expression data in the various translocations ...

Eligibility Criteria

Inclusion

  • Enrolled on CALGB acute myeloid leukemia (AML) treatment studies AND concurrently enrolled on Leukemia Tissue Bank Protocol CALGB-9665
  • Short-term or long-term survivor
  • Bone marrow and/or peripheral blood obtained at diagnosis
  • Leukemia is one of the following cytogenetic subtypes:
  • t(8;21)
  • t(15;17)
  • inv(16)

Exclusion

    Key Trial Info

    Start Date :

    May 1 2008

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    March 1 2014

    Estimated Enrollment :

    96 Patients enrolled

    Trial Details

    Trial ID

    NCT00897182

    Start Date

    May 1 2008

    End Date

    March 1 2014

    Last Update

    July 4 2016

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Fort Wayne Medical Oncology and Hematology

    Fort Wayne, Indiana, United States, 46845

    2

    Wayne Memorial Hospital, Incorporated

    Goldsboro, North Carolina, United States, 27534

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