Status:

COMPLETED

Blood Samples From Patients With Non-Small Cell Lung Cancer and From Healthy Volunteers

Lead Sponsor:

University of Minnesota

Conditions:

Lung Cancer

Eligibility:

All Genders

18+ years

Brief Summary

RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This r...

Detailed Description

OBJECTIVES: * Measure plasma cathepsin D levels in patients with non-small cell lung cancer and in healthy volunteers using mass spectometry. * Measure fatty acid synthase levels in these patients an...

Eligibility Criteria

Inclusion

  • Non-Small Cell Lung Cancer Patients
  • Documented diagnosis of non-small cell lung cancer, any stage and any time point in the course of treatment (i.e., at diagnosis, during any treatment, and during post treatment surveillance)
  • Measurable disease by CT scan within the past 4 weeks
  • Healthy volunteer
  • Non-smoking, defined as \< 5 packs/year history of smoking and cessation of smoking ≥ 6 months ago OR a never smoker
  • Not regularly exposed (i.e., daily) to second-hand smoke

Exclusion

  • Severe underlying lung disease (i.e., chronic obstructive pulmonary disease with FEV\_1 \< 1.0 L, pulmonary fibrosis, bronchiectasis, cystic fibrosis, etc.) as determined by enrolling researcher.
  • Written consent must be given for both subjects and controls.

Key Trial Info

Start Date :

December 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2010

Estimated Enrollment :

84 Patients enrolled

Trial Details

Trial ID

NCT00897234

Start Date

December 1 2008

End Date

October 1 2010

Last Update

August 22 2014

Active Locations (1)

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Masonic Cancer Center at University of Minnesota

Minneapolis, Minnesota, United States, 55455