Status:

COMPLETED

Biomarkers to Detect Mesothelioma Early in Patients Exposed to Asbestos or Vermiculite

Lead Sponsor:

Barbara Ann Karmanos Cancer Institute

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Malignant Mesothelioma

Pulmonary Complications

Eligibility:

All Genders

25-80 years

Brief Summary

RATIONALE: Studying samples of body fluid and blood from patients who have been exposed to asbestos or vermiculite in the laboratory may help doctors learn more about changes that may occur in DNA and...

Detailed Description

OBJECTIVES: * Identify patients with known asbestos exposure at early stages of disease development (i.e., indolent premalignant pleural plaques and fibrosis vs malignant pleural mesothelioma). * Det...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Exposure to vermiculite or asbestos insulation
  • Symptomatic or nonsymptomatic exposure-related disease
  • Seen at a clinic in Libby, Montana (CARD Clinic) or Michigan (COEM)
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Not specified

Exclusion

    Key Trial Info

    Start Date :

    January 1 2007

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    October 1 2013

    Estimated Enrollment :

    494 Patients enrolled

    Trial Details

    Trial ID

    NCT00897247

    Start Date

    January 1 2007

    End Date

    October 1 2013

    Last Update

    March 5 2014

    Active Locations (1)

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    Barbara Ann Karmanos Cancer Institute

    Detroit, Michigan, United States, 48201-1379