Status:

TERMINATED

Effect of Biological Therapy on Biomarkers in Patients With Untreated Hepatitis C, Metastatic Melanoma, or Crohn Disease

Lead Sponsor:

Vanderbilt-Ingram Cancer Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Melanoma

Eligibility:

All Genders

Brief Summary

RATIONALE: Studying samples of blood from patients with cancer, hepatitis C, or Crohn disease in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers rela...

Detailed Description

OBJECTIVES: * To determine how a variety of immune-modulating therapies (i.e., interferon alfa \[IFN-α\] in patients with untreated acute or chronic hepatitis C, anti-tumor necrosis factor in patient...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Diagnosis of 1 of the following:
  • Acute or chronic hepatitis C
  • Receiving pegylated interferon alfa and ribavirin
  • Metastatic melanoma
  • Receiving ticilimumab
  • Crohn disease
  • Received prior infliximab

Exclusion

  • Not specified
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Key Trial Info

Start Date :

October 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2008

Estimated Enrollment :

7 Patients enrolled

Trial Details

Trial ID

NCT00897312

Start Date

October 1 2006

End Date

August 1 2008

Last Update

April 25 2016

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