Status:

COMPLETED

Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Recurrent Adult Acute Lymphoblastic Leukemia

Recurrent Adult Non-Hodgkin Lymphoma

Eligibility:

All Genders

Up to 30 years

Brief Summary

This research study is collecting and storing samples of bone marrow and blood from patients with relapsed acute lymphoblastic leukemia or relapsed non-Hodgkin lymphoma. Collecting and storing samples...

Detailed Description

OBJECTIVES: I. Establish a mechanism to bank specimens of tumor cells and host germline DNA from patients with acute lymphoblastic leukemia (ALL) at first and subsequent relapse. II. Make these spec...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Diagnosis of acute lymphoblastic leukemia (ALL) or prior history of non-Hodgkin lymphoma
  • In first or subsequent marrow relapse with ≥ 25% blasts in bone marrow and/or peripheral blood
  • Bone marrow and/or peripheral blood samples (≥ 5 mL) required at the time of diagnosis of relapse
  • No concurrent systemic antileukemic treatment administered for current relapse
  • Intrathecal chemotherapy allowed
  • On-therapy relapse allowed

Exclusion

    Key Trial Info

    Start Date :

    September 25 2006

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    December 31 2019

    Estimated Enrollment :

    811 Patients enrolled

    Trial Details

    Trial ID

    NCT00897325

    Start Date

    September 25 2006

    End Date

    December 31 2019

    Last Update

    January 18 2020

    Active Locations (183)

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    Page 1 of 46 (183 locations)

    1

    Children's Hospital of Alabama

    Birmingham, Alabama, United States, 35233

    2

    University of Alabama at Birmingham Cancer Center

    Birmingham, Alabama, United States, 35233

    3

    Phoenix Childrens Hospital

    Phoenix, Arizona, United States, 85016

    4

    Banner University Medical Center - Tucson

    Tucson, Arizona, United States, 85719