Status:

TERMINATED

Treatment Strategy for Low-grade Gliomas

Lead Sponsor:

Sun Yat-sen University

Conditions:

Astrocytomas

Oligodendrogliomas

Eligibility:

All Genders

18-60 years

Phase:

PHASE3

Brief Summary

Although the prognosis of patients with low-grade glioma (LGG) is generally good, recurrence seems unavoidable in some patients because of the infiltrative growth of the tumors. How to treat LGGs is s...

Eligibility Criteria

Inclusion

  • Histologically confirmed newly diagnosed low-grade gliomas
  • Karnofsky performance status of 60 or more

Exclusion

  • Previous history of radiation therapy or chemotherapy for gliomas
  • Pregnant or breast feeding
  • Diagnosis of another malignancy may exclude subject from study
  • Evidence or history of bleeding diathesis
  • Evidence or history of hypersensitivity to temozolomide

Key Trial Info

Start Date :

December 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT00897377

Start Date

December 1 2007

Last Update

August 5 2014

Active Locations (1)

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1

Sun Yat-sen University

Guangzhou, Guangdong, China, 510060