Status:

COMPLETED

Study of DNA in Blood Samples From Patients With Neuroblastoma

Lead Sponsor:

Children's Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Disseminated Neuroblastoma

Localized Resectable Neuroblastoma

Eligibility:

All Genders

Brief Summary

This research trial studies is deoxyribonucleic acid (DNA) in blood samples from patients with neuroblastoma. Studying samples of blood from patients with cancer in the laboratory may help doctors lea...

Detailed Description

OBJECTIVES: I. Perform in a blind study a multicentric study by analyzing serum from patients at diagnosis (with a known tumor v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolo...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Serum samples from neuroblastoma (NB) patients obtained through the COG (and legacy Children's Cancer Group \[CCG\]/Pediatric Oncology Group \[POG\] Biology Studies)
  • The MYCN status on corresponding tumors have been determined using standard techniques; the panel of samples must be obtained from NB patients with and without MYCN amplification tumors
  • Cases will be drawn from clinical subsets at greatest likelihood to benefit from this testing ability, stage 1 and 2 NBs (both infants and toddlers), stage 4 patients under 18 months of age, and 4S patients

Exclusion

    Key Trial Info

    Start Date :

    June 1 2007

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    May 1 2016

    Estimated Enrollment :

    329 Patients enrolled

    Trial Details

    Trial ID

    NCT00898391

    Start Date

    June 1 2007

    End Date

    May 1 2016

    Last Update

    May 18 2016

    Active Locations (1)

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    Children's Oncology Group

    Monrovia, California, United States, 91006-3776